Carbamyl Chlorides
Carbamyl Chlorides
Carbamyl chlorides, also referred to as carbamoyl chlorides, have the functional group R2NC(=O)Cl. When compared to acid chloride, these compounds are less sensitive hydrolytically largely due to the influence of amino group. Carbamoyl chlorides are useful reagents for the preparation of a number of agricultural compounds. For instance they are useful intermediates in the preparation of herbicides such as thiolcarbamate which involve their reaction with thiols. In the field of pharmaceuticals, N-ethyl-N-methylcarbamoyl chloride and N,N- diethylcarbamoyl chloride have been used in the preparation of parasympathomimetic and antifilarial drugs respectively, as intermediates. Besides pharmaceuticals, they also find application in the production of dyes and peroxides.
